At SphinCS we have organised our activities distributed over two entities: SphinCS and SphinCSLyso. We are a specialized team with extensive knowledge and experience in the field of LSDs, led by Dr. Eugen Mengel and Petra Kleinhans. The patron is Prof. Michael Beck.
The international research in the field of LSDs was co-designed and advanced by Prof. Dr. Beck and Dr. Eugen Mengel (photo). In the last 25 years, therapies have been approved for 9 (of > 50) LSDs. Prof. Dr. Beck and Dr. Mengel were significantly involved in 8 diseases.
As an independent institute for clinical research in the field of LSD, our focus is on promising new drugs for LSDs at a high level in all phases and aspects of clinical research.
We want to give German speaking patients the opportunity to participate in future studies with new drugs.
We pursue the concept that patients play an active role in clinical research. Cooperation with self-help groups is an essential aspect of our approach.
Principle investigator, founder and CEO of the SphinCS GmbH & SphinCS Lyso non-profit UG. Dr. Mengel has dedicated himself to research in the field of LSDs, and has already significantly contributed to the advancement of this field of study.
Prof. Dr. Beck has a broad scientific background in: medicine, paediatrics, biochemistry and human genetics. He has been influential internationally in progressing the field of study of LSDs. At SphinCS he works as a consultant.
Petra Kleinhans is a registered specialist paediatric nurse and has been working in the field of lysosomal storage disorders for over 16 years. During this time, she has developed her expertise in phase I-IV clinical trials. In addition to study coordination and study management, project development is one of her main activities.
At the Hochheim site, the co-founder of SphinCS organises studies of rare to ultra-rare diseases.
Mrs. Dr. Amraoui has 15 years of expertise in the diagnosis, care and treatment of patients with lysosomal storage disorders, which she acquired during her work as a specialist in paediatrics and adolescent medicine at the University Medical Center Mainz. Ms. Dr. Amraoui participated as an investigator in more than 30 clinical trials and was instrumental in the research of various lysosomal storage disorders and the approval of various drugs. In October 2019 Dr. Amraoui has joined the SphinCS team as a highly experienced investigator. In addition to leading and conduction of clinical trials, her activities include project development.
After completing her medicine study at the Mexican University Michoacan of Saint Nicholas of Hidalgo, Ms. Rios worked as an emergency doctor. She joined the SphinCS team in 2020.
Loreen Gramsch is a certified pediatric nurse and completed a 1/2 year training as a study assistant in the year 2011. In 2009 she worked as a study coordinator in phase I-IV in clinical trials. In the last 4 years, she has acquired a high level of professional competence in the field of lysosomal memory diseases.
In April 2020, Ms. Gramsch has joined the SphinCS team with her expertise as a study coordinator. In addition to the coordination and conduct of clinical trials, their activities include project development.
Dr. Schädlich started her education at the Paediatric Nursing School Johannes-Gutenberg Mainz. She is a qualified medical doctor involved in clinical research since 2016.